Despite all the options available to enhance the flexibility of a work, including PUR adhesive, sewing, freehand binding (Layflat or Otabind), and respecting the grain direction, a work bound with adhesive (thermal binding) has certain constraints.
Too often, we see designs poorly adapted to the type of binding. Texts ending up 1/8 inch from the spine, Spreads (images or text flowing between two consecutive pages) with important details and titles in the joint, or folios 1/16 inch from the cut.
When a job is bound on a gluer, there may be dozens of signatures assembled at the same time. All these signatures (sections or booklets) have experienced some variation in folding and/or assembly. Certain adjustments must be made with a three-sided knife to avoid cutting into the folios or clearing the Spreads. When the design is well executed, these adjustments are not noticeable, but if the design leaves no room for maneuver, everyone can see it!
Make sure that the information in the center is not critical to prevent the reader from feeling the need to undo the binding to see the missing detail!
Do not hesitate to have your design validated by a binder specializing in thermal binding.